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Organic Raw Whole Food Supplements

Antioxidant properties of novel phycocyanin extract from the blue-green alga Aphanizomenon flos-aquae

Life Sciences 75 (2004) 2353-2362

Author(s): Serena Benedetti, Francesca Benvenuti, Silvia Pagliarani, Sonia Francogli, Stefano Scoglio, Franco Canestrari

ABSTRACT

Aphanizomenon flos-aquae (AFA) is a fresh water unicellular blue-green alga (cyanophyra) rich in phycocyanin (PC), a photosynthetic pigment with antioxidant and anti-inflammatory properties.

The purpose of this study was to evaluate the ability of a novel natural extract from AFA enriched with PC to project normal human erythrocytes and plasma samples against oxidative damage in vitro. In red blood cells, oxidative hemolysis and lipid peroxidation induced by the aqueous peroxyl radical generator [2, 2'-Azobis (2-amidinopropane) dihydrochloride, AAPH] were significantly lowered by the AFA extract in a time- and dose-dependent manner; at the same time, the depletion of cytosolic glutathione was delayed. In plasma samples, the natural extract inhibited the extent of lipid oxidation induced by the pro-oxidant agent cupric chloride (CuC12); a concomitant increase of plasma resistance to oxidation was observed as evaluated by conjugated diene formation.

The involvement of PC in the antioxidant protection of the APA extract against the oxidative damage was demonstrated by investigating the spectra changes of PC induced by AAPH or CuC12. The incubation of the extract with the oxidizing agents led to a significant decrease in the absorption of PC at 620 nm accompanied with disappearance of it blue color, thus indicating a rapid oxidation of the protein. In the light of these in vitro results, the potential clinical applications of this natural compound are under investigation.

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TESTIMONIES

"We are so excited about the Bluegree Body Algae. We´ve seen some real benefits for the immune systems of animals. We had a 12 year old dog brought into the clinic who had been hit by a car. We decided to start him eating Bluegreen Body and the Enzymes. The dog had to be in a splint for 3 weeks. Every week when he came in to be checked he was looking better and better. His condition and haircut were improving. By the third week his owner was so impressed she started using the same supplements. The dog´s attitude is wonderful. The day he was brought in he bit one of the techs and he didn´t want anyone to do anything to him. After a couple of days, even though he was still very sore, there was a major improvement in his behavior. Now when he comes in he even kisses everyone. We also do short nail clips for show dogs. I decided to try sprinkling algae on nails that we quickened to see its effect. It did a wonderful job - so we have switched!"
- Dr. Ron Bowen, DVM and Dr. Debby Dowen, DVM
Chicago, Illinois

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